[Bone marrow necrosis. A case report].

The bone marrow is one of the largest organs in the human body (Lund, 2000). It is the major hematopoietic organ and is important as both a primary and secondary lymphoid organ. Since it is a potential target organ of various disorders, evaluation of blood and bone marrow is an important component of any overall assessment studies. Bone marrow evaluation studies provide information about bone marrow tissue architecture like cellularity, cell lineages, vascular or stromal alterations, inflammation or necrosis. When it is used in conjunction with a complete blood count, the histological examination of bone marrow provides information regarding the hematopoietic system that might otherwise be missed by examination of peripheral blood smear alone. Bone marrow is rarely affected by various disorders like metastatic tumors storage disorders, leukemia, lymphomas, etc. Few such lesions result in necrosis of bone marrow. This signals bad prognosis. The various disorders which affect the bone marrow are leukemias, lymphomas, storage disorders, tuberculosis, metastatic deposits, and fungal infections. We report a case of 65-year-old female who underwent bone marrow biopsy. Histological features were consistent with necrosis of bone marrow.